Chembl377829

Chemical Properties

SMILES Cc1cccc(NC(=O)c2cccc(Cl)c2)n1
Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight 246.1

Drug Properties

Type Small molecule
Endogenous No
Approved No
InChIKey HNLLGNJHYQMYEI-UHFFFAOYSA-N

Database Connections

External Links


Bioactivity

Receptor Experimental Data Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Rat Metabotropic glutamate C pIC50 5.73 5.83 5.93 ChEMBL
mGlu5 GRM5 Rat Metabotropic glutamate C pKi 5.76 5.76 5.76 ChEMBL