Chembl3800165


SMILES CCCN[C@@H]1Cc2cccc3c2n(c(=O)n3CCC)C1
InChIKey FHJKGVBVLIXGIQ-CYBMUJFWSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 273.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections


Bioactivity

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pKi 7.32 7.49 7.66 ChEMBL
D3 DRD3 Human Dopamine A pEC50 5.85 6.55 7.25 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.06 7.07 8.09 ChEMBL
D2 DRD2 Human Dopamine A pEC50 7.17 7.53 7.89 ChEMBL