CHEMBL3894679


SMILES O=C(CCOCCN1CCN(c2ncccc2-c2ccc(F)cc2)CC1)NCc1ccc(C(F)(F)F)cc1
InChIKey AOLMBJPDPWHRDR-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 10
Molecular weight (Da) 530.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.5 7.5 7.5 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 5.97 5.97 5.97 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.74 5.74 5.74 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.41 6.41 6.41 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database