Chembl390603

Chemical Properties

SMILES Cc1c(Cl)cccc1S(=O)(=O)N[C@H](CC(=O)N[C@@H]1CCOc2cc(CNC(C)(C)C)ccc21)c1ccccc1
Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 9
Molecular weight 569.2

Drug Properties

Type Small molecule
Endogenous No
Approved No
InChIKey RFZOXQFIPGWDKX-CLJLJLNGSA-N

Database Connections

External Links


Bioactivity

Receptor Experimental Data Source
GTP Uniprot Species Family Class Type Min Avg Max Database
B1 BKRB1 Human Bradykinin A pKi 7.39 7.39 7.39 ChEMBL
B1 BKRB1 Human Bradykinin A pIC50 6.68 6.68 6.68 ChEMBL