CHEMBL3774769


SMILES Cn1c(SCCCN2CC3CCN(c4ccc(C(F)(F)F)cc4)C3C2)nnc1-c1ccc(=O)n(C)c1
InChIKey STIWHEMFVTWALB-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 8
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 518.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 6.32 6.32 6.32 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 6.42 6.42 6.42 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.2 8.23 8.3 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.8 6.1 6.3 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database