CHEMBL39230


SMILES CCCc1cc2c(s1)CN[C@H]1CCc3cc(O)c(O)cc3[C@H]21
InChIKey REHAKLRYABHSQJ-KBXCAEBGSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 2
Molecular weight (Da) 315.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Rat Dopamine A pKi 6.19 6.97 7.75 ChEMBL
D1 DRD1 Human Dopamine A pKi 5.52 5.52 5.52 ChEMBL
D2 DRD2 Rat Dopamine A pKi 5.27 5.56 5.85 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.4 5.4 5.4 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Goldfish Dopamine A pEC50 5.57 6.43 7.28 ChEMBL
D1 DRD1 Human Dopamine A pEC50 5.77 5.77 5.77 ChEMBL