CHEMBL3799801


SMILES COc1nc(C)c(Nc2nc(Cl)cn([C@H](COc3cc(C#N)ccn3)C3CC3)c2=O)cc1C
InChIKey PLBUBFRSQTYXBK-GOSISDBHSA-N

Chemical properties

Hydrogen bond acceptors 9
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 466.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CRF1 CRFR1 Rat Corticotropin-releasing factor B1 pIC50 8.17 8.17 8.17 ChEMBL