CHEMBL3818805


SMILES O=c1[nH]c2cc(Cl)ccc2n1C1CCN(CCCCc2c[nH]c3ccccc23)CC1
InChIKey ADUYXHYSTCIMEO-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 6
Molecular weight (Da) 422.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.95 6.96 6.96 ChEMBL
H1 HRH1 Human Histamine A pKi 6.59 6.6 6.61 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.79 7.79 7.8 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 7.29 7.29 7.29 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.28 7.29 7.3 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.87 6.87 6.87 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database