CHEMBL385722


SMILES C[C@@H]1CN(c2ccc(Nc3c(CO)cnc4ccccc34)cc2)CCN1
InChIKey MDMIXTNJRVJFQM-OAHLLOKOSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 4
Molecular weight (Da) 348.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pKi 4.75 4.75 4.75 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 6.69 6.69 6.69 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 5.02 5.02 5.02 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database