CHEMBL3892492


SMILES O=C(O)c1ccc(CC[C@H]2C(=O)CC[C@@H]2/C=C/C(O)Cc2ccc(F)cc2)cc1
InChIKey TZVFTSQQDVXJEF-HPILLFOASA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 8
Molecular weight (Da) 396.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP2 PE2R2 Human Prostanoid A pKi 5.03 5.58 6.13 ChEMBL
EP4 PE2R4 Human Prostanoid A pKi 6.04 7.28 8.52 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP2 PE2R2 Human Prostanoid A pEC50 7.96 7.96 7.96 ChEMBL
EP3 PE2R3 Human Prostanoid A pEC50 6.02 6.02 6.02 ChEMBL
EP4 PE2R4 Human Prostanoid A pEC50 7.42 8.56 9.7 ChEMBL
TP TA2R Human Prostanoid A pEC50 5.25 5.25 5.25 ChEMBL