CHEMBL394732
SMILES | Clc1ccc(C2CNCc3cc(OCCCN4CCCCC4)ncc32)cc1Cl |
InChIKey | RTXNVJXREKUAHX-UHFFFAOYSA-N |
Chemical properties
Hydrogen bond acceptors | 4 |
Hydrogen bond donors | 1 |
Rotatable bonds | 6 |
Molecular weight (Da) | 419.2 |
Drug properties
Molecular type | Small molecule |
Endogenous/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
H3 | HRH3 | Human | Histamine | A | pKd | 7.95 | 7.95 | 7.95 | ChEMBL |
H3 | HRH3 | Human | Histamine | A | pKi | 8.3 | 8.3 | 8.3 | ChEMBL |
H3 | HRH3 | Human | Histamine | A | pKi | 8.3 | 8.3 | 8.3 | PDSP Ki database |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |