ecopipam


SMILES CN1CCc2c([C@@H]3[C@@H]1CCc1c3cccc1)cc(c(c2)Cl)O
InChIKey DMJWENQHWZZWDF-PKOBYXMFSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 0
Molecular weight (Da) 313.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Human Dopamine A pKi 8.3 8.3 8.3 Guide to Pharmacology
D5 DRD5 Human Dopamine A pKi 8.3 8.3 8.3 Guide to Pharmacology
D5 DRD5 Human Dopamine A pKi 8.7 8.7 8.7 ChEMBL
D1 DRD1 Human Dopamine A pKi 8.72 8.87 9.05 ChEMBL
D2 DRD2 Rat Dopamine A pKi 6.29 6.29 6.29 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.91 5.98 6.01 ChEMBL
D4 DRD4 Human Dopamine A pKi 5.26 5.26 5.26 ChEMBL
D1 DRD1 Rat Dopamine A pKi 8.72 8.72 8.72 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Human Dopamine A pIC50 8.82 8.82 8.82 ChEMBL
TSH TSHR Human Glycoprotein hormone A Potency 4.8 4.8 4.8 ChEMBL