CHEMBL3958215


SMILES O=C1c2ccc(F)cc2CC1CCN1CCc2ccccc2C1
InChIKey QIGRVQBAYKSEIV-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 309.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Rat Dopamine A pKi 6.6 6.6 6.6 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 8.8 8.8 8.8 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.53 6.53 6.53 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.72 7.72 7.73 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.92 5.92 5.92 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.65 6.65 6.65 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.12 6.12 6.12 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database