Chembl3964349

Chemical Properties

SMILES CCOc1cccc(F)c1[C@@H]1C[C@H](F)C(=O)N1Cc1ccc(OC(F)(F)F)c(Cl)c1
Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight 449.1

Drug Properties

Type Small molecule
Endogenous No
Approved No
InChIKey QWQQJMSWYYTSLP-GJZGRUSLSA-N

Database Connections

External Links


Bioactivity

Receptor Experimental Data Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Human Orexin A pIC50 6.14 6.14 6.14 ChEMBL
OX2 OX2R Human Orexin A pIC50 8.4 8.4 8.4 ChEMBL