Chembl3970701

Chemical Properties

SMILES O=C1N[C@H](c2cncc(C#C[C@H]3C[C@@H](O)C3)c2)[C@@H](c2cccc(F)c2)O1
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 2
Molecular weight 352.1

Drug Properties

Type Small molecule
Endogenous No
Approved No
InChIKey IZDJAZZKINJIGM-YJQAKTFBSA-N

Database Connections

External Links

Bioactivity

Receptor Experimental Data Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Human Metabotropic glutamate C pKi 6.15 6.15 6.15 ChEMBL
mGlu5 GRM5 Human Metabotropic glutamate C pEC50 6.6 6.6 6.6 ChEMBL