[Leu31,Pro34]NPY (pig)


SMILES None
InChIKey None
Sequence YPSKPDNPGEDAPAEDLARYYSALRHYINLLTRPRY

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Peptide
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.8 6.8 6.8 Guide to Pharmacology
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 6.5 6.5 6.5 Guide to Pharmacology
5-HT5A 5HT5A Human 5-Hydroxytryptamine A pKi 5.3 5.3 5.3 Guide to Pharmacology
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 7.8 7.8 7.8 Guide to Pharmacology
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.5 6.5 6.5 Guide to Pharmacology
5-HT1E 5HT1E Human 5-Hydroxytryptamine A pKi 6.28 6.28 6.28 ChEMBL
5-HT2C 5HT2C Rat 5-Hydroxytryptamine A pKi 5.74 5.74 5.74 ChEMBL
5-HT5A 5HT5A Human 5-Hydroxytryptamine A pKi 5.33 5.33 5.33 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 6.54 6.54 6.54 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.52 6.52 6.52 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 7.28 7.75 7.8 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.77 6.77 6.77 ChEMBL
5-HT1E 5HT1E Human 5-Hydroxytryptamine A pKi 6.3 6.3 6.3 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pIC50 5.85 5.85 5.85 ChEMBL
5-HT4 5HT4R Guinea pig 5-Hydroxytryptamine A pIC50 7.36 7.36 7.36 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pIC50 5.82 5.82 5.82 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pIC50 7.07 7.07 7.07 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pIC50 5.26 5.26 5.26 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pIC50 6.21 6.21 6.21 ChEMBL