[Leu31,Pro34]PYY (human)
SMILES | None |
InChIKey | None |
Sequence | YPIKPEAPGEDASPEELNRYYASLRHYLNLLTRPRY |
Chemical properties
Hydrogen bond acceptors | None |
Hydrogen bond donors | None |
Rotatable bonds | None |
Molecular weight (Da) |
Drug properties
Molecular type | Peptide |
Endogenous/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
κ | OPRK | Human | Opioid | A | pKi | 9.6 | 9.6 | 9.6 | Guide to Pharmacology |
κ | OPRK | Human | Opioid | A | pKd | 8.6 | 8.9 | 9.2 | Guide to Pharmacology |
κ | OPRK | Rat | Opioid | A | pKi | 10.0 | 10.0 | 10.0 | ChEMBL |
μ | OPRM | Rat | Opioid | A | pKi | 7.06 | 7.06 | 7.06 | ChEMBL |
κ | OPRK | Human | Opioid | A | pKi | 9.57 | 9.57 | 9.57 | ChEMBL |
δ | OPRD | Human | Opioid | A | pKi | 6.0 | 6.0 | 6.0 | PDSP Ki database |
κ | OPRK | Human | Opioid | A | pKi | 9.57 | 9.57 | 9.57 | PDSP Ki database |
μ | OPRM | Human | Opioid | A | pKi | 7.66 | 7.66 | 7.66 | PDSP Ki database |
μ | OPRM | Human | Opioid | A | pKi | 7.66 | 7.66 | 7.66 | ChEMBL |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
κ | OPRK | Human | Opioid | A | pEC50 | 8.48 | 8.48 | 8.48 | ChEMBL |