Chembl3990537

Chemical Properties

SMILES NC(=O)c1cccc([C@@H]2C[C@@H]3CC[C@H](C2)N3CCN(Cc2c(F)cccc2F)C(=O)[C@H](O)CO)c1
Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 9
Molecular weight 487.2

Drug Properties

Type Small molecule
Endogenous No
Approved No
InChIKey YIJXZOJTKRAPAH-ZBNTXBBCSA-N

Database Connections

External Links


Bioactivity

Receptor Experimental Data Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Guinea pig Opioid A pKi 7.0 7.0 7.0 ChEMBL
δ OPRD Human Opioid A pKi 7.0 7.0 7.0 ChEMBL
μ OPRM Human Opioid A pKi 8.0 8.0 8.0 ChEMBL