CHEMBL399495


SMILES C[C@@H](NC(=O)Nc1cccc(-c2nnnn2C)c1)[C@@H](O)CN1CCC[C@@H](Cc2ccc(F)cc2)C1
InChIKey JTVSGNGYUGCQJP-FHJLPGHOSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 3
Rotatable bonds 8
Molecular weight (Da) 481.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CCR3 CCR3 Crab-eating macaque Chemokine A pIC50 9.82 9.82 9.82 ChEMBL
CCR3 CCR3 Human Chemokine A pIC50 9.06 9.69 10.42 ChEMBL
CCR3 CCR3 Mouse Chemokine A pIC50 7.51 7.51 7.51 ChEMBL