CHEMBL4060567


SMILES N[C@@]1(C(=O)O)C[C@H](NC(=O)C2CCCCC2)[C@H]2[C@H](C(=O)O)[C@H]21
InChIKey URPILZHDNHGJFA-DMZJWBPISA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 4
Rotatable bonds 4
Molecular weight (Da) 310.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu3 GRM3 Human Metabotropic glutamate C pKi 6.12 6.12 6.12 ChEMBL
mGlu2 GRM2 Human Metabotropic glutamate C pKi 5.82 5.82 5.82 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu3 GRM3 Human Metabotropic glutamate C pIC50 5.0 5.0 5.0 ChEMBL
mGlu2 GRM2 Human Metabotropic glutamate C pIC50 4.92 4.92 4.92 ChEMBL
mGlu2 GRM2 Human Metabotropic glutamate C pEC50 5.47 5.47 5.47 ChEMBL