Chembl4064589

Chemical Properties

SMILES FC(F)(F)c1c(-c2ccc(NC3CCOCC3)c(Cl)c2)ccn2c(CC3CC3)nnc12
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight 450.1

Drug Properties

Type Small molecule
Endogenous No
Approved No
InChIKey XQCCADHVKCTQDD-UHFFFAOYSA-N

Database Connections

External Links


Bioactivity

Receptor Experimental Data Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu2 GRM2 Human Metabotropic glutamate C pKd 8.42 8.42 8.42 ChEMBL
mGlu2 GRM2 Human Metabotropic glutamate C pEC50 7.73 7.73 7.73 ChEMBL
mGlu2 GRM2 Human Metabotropic glutamate C pKi 8.3 8.3 8.3 ChEMBL