ethylisopropylamiloride
| SMILES | CCN(c1nc(N)c(nc1Cl)C(=O)N=C(N)N)C(C)C |
| InChIKey | QDERNBXNXJCIQK-UHFFFAOYSA-N |
Chemical properties
| Hydrogen bond acceptors | 5 |
| Hydrogen bond donors | 3 |
| Rotatable bonds | 4 |
| Molecular weight (Da) | 299.1 |
Drug properties
| Molecular type | Small molecule |
| Endogenous/Surrogate | Surrogate |
| Approved drug | No |
Database connections
Bioactivities
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| α2A | ADA2A | Human | Adrenoceptors | A | pKd | 1.8 | 1.8 | 1.8 | Guide to Pharmacology |
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| 5-HT5A | 5HT5A | Human | 5-Hydroxytryptamine | A | pEC50 | 4.07 | 4.07 | 4.07 | ChEMBL |
| δ | OPRD | Human | Opioid | A | pEC50 | 4.19 | 4.19 | 4.19 | ChEMBL |
| TSH | TSHR | Human | Glycoprotein hormone | A | Potency | 4.7 | 4.7 | 4.7 | ChEMBL |
| M1 | ACM1 | Rat | Acetylcholine (muscarinic) | A | Potency | 5.1 | 5.1 | 5.1 | ChEMBL |