CHEMBL3950020


SMILES O=C(CCOCCN1CCN(c2ncccc2-c2ccccc2)CC1)NCc1ccc(C(F)(F)F)cc1
InChIKey HPLCRGYHYQJALL-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 10
Molecular weight (Da) 512.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.28 7.28 7.28 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 5.98 5.98 5.98 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.44 6.44 6.44 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.57 6.57 6.57 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database