SR142948A


SMILES COc1cccc(c1c1cc(nn1c1ccc(cc1C(C)C)C(=O)N(CCCN(C)C)C)C(=O)NC1(C(=O)O)C2CC3CC1CC(C2)C3)OC
InChIKey LWULHXVBLMWCHO-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 8
Hydrogen bond donors 2
Rotatable bonds 13
Molecular weight (Da) 685.4

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Structure pdb 6Z4Q

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
GPR6 GPR6 Human A orphans A pIC50 8.7 8.7 8.7 Guide to Pharmacology
GPR6 GPR6 Human A orphans A pIC50 8.7 8.7 8.7 ChEMBL