CHEMBL3961059


SMILES CNCc1ccc(Cl)c(-c2ccccc2OC)c1
InChIKey NSASZAUFRUOUIN-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 261.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1E 5HT1E Human 5-Hydroxytryptamine A pKi 5.62 5.62 5.62 ChEMBL
5-HT5A 5HT5A Human 5-Hydroxytryptamine A pKi 6.38 6.38 6.38 ChEMBL
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 5.92 5.92 5.92 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 5.92 5.92 5.92 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 8.28 8.28 8.28 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 5.89 5.89 5.89 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 7.89 7.89 7.89 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.7 6.7 6.7 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.42 6.42 6.42 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.77 5.77 5.77 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pEC50 6.26 6.48 6.83 ChEMBL