Chembl4099840

Chemical Properties

SMILES COC(=O)N1CCN(C(=O)Cc2ccc(Cl)c(Cl)c2)[C@@H]2[C@@H](N3CC[C@@H](O)C3)CCC[C@@H]21
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight 469.2

Drug Properties

Type Small molecule
Endogenous No
Approved No
InChIKey BEWAPTMRQKYOSC-PXDUREFJSA-N

Database Connections

External Links


Bioactivity

Receptor Experimental Data Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Guinea pig Opioid A pKi 8.89 8.89 8.89 ChEMBL
κ OPRK Human Opioid A pEC50 8.33 8.33 8.33 ChEMBL