CHEMBL4098803


SMILES COc1ccccc1N1CCN(CCCCOc2ccc3ccnn3c2)CC1
InChIKey VIESVSSRMWPJQT-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 8
Molecular weight (Da) 380.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Human Dopamine A pKi 5.96 5.96 5.96 ChEMBL
D4 DRD4 Human Dopamine A pKi 9.16 9.16 9.16 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.68 6.68 6.68 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.3 8.3 8.3 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.74 8.94 9.13 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pEC50 7.54 7.54 7.54 ChEMBL
D2 DRD2 Human Dopamine A pEC50 7.64 8.33 8.82 ChEMBL