Chembl4106552

Chemical Properties

SMILES C[C@@H]1CN(Cc2ccc3c(-c4cn[nH]c4)cc(C(N)=O)nc3c2)C[C@H](C(F)(F)F)O1
Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 4
Molecular weight 419.2

Drug Properties

Type Small molecule
Endogenous No
Approved No
InChIKey KSNGKFZHOBHQPZ-ADLMAVQZSA-N

Database Connections

External Links


Bioactivity

Receptor Experimental Data Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu2 GRM2 Human Metabotropic glutamate C pIC50 6.58 6.58 6.58 ChEMBL