5-butyl-1H-pyrazole-3-carboxylic acid
SMILES | CCCCc1cc(n[nH]1)C(=O)O |
InChIKey | ZJTXSGLJNBAMJS-UHFFFAOYSA-N |
Chemical properties
Hydrogen bond acceptors | 2 |
Hydrogen bond donors | 2 |
Rotatable bonds | 4 |
Molecular weight (Da) | 168.1 |
Drug properties
Molecular type | Small molecule |
Physiological/Surrogate | Surrogate |
Approved drug | No |
Database connections
Structure pdb | 8IHH |
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
HCA2 | HCAR2 | Rat | Hydroxycarboxylic acid | A | pKi | 7.1 | 7.1 | 7.1 | Guide to Pharmacology |
HCA2 | HCAR2 | Rat | Hydroxycarboxylic acid | A | pKi | 7.14 | 7.14 | 7.14 | ChEMBL |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
HCA3 | HCAR3 | Human | Hydroxycarboxylic acid | A | pEC50 | 4.93 | 4.93 | 4.93 | ChEMBL |
HCA2 | HCAR2 | Human | Hydroxycarboxylic acid | A | pEC50 | 5.85 | 6.46 | 7.07 | ChEMBL |