fenoterol


SMILES CC(Cc1ccc(cc1)O)NCC(c1cc(O)cc(c1)O)O
InChIKey LSLYOANBFKQKPT-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 5
Rotatable bonds 6
Molecular weight (Da) 303.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
β2 ADRB2 Human Adrenoceptors A pKi 6.9 6.9 6.9 Guide to Pharmacology
β2 ADRB2 Human Adrenoceptors A pKd 6.86 6.93 7.0 ChEMBL
β2 ADRB2 Human Adrenoceptors A pKi 6.9 6.9 6.9 ChEMBL
β2 ADRB2 Guinea pig Adrenoceptors A pKi 6.29 6.3 6.31 PDSP Ki database
β1 H0W3H1 Guinea pig Adrenoceptors A pKi 5.38 5.38 5.38 PDSP Ki database
β1 ADRB1 Human Adrenoceptors A pKi 5.0 5.0 5.0 PDSP Ki database
β2 ADRB2 Human Adrenoceptors A pKi 6.14 6.14 6.14 PDSP Ki database
β3 ADRB3 Human Adrenoceptors A pKi 5.0 5.0 5.0 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
β2 ADRB2 Guinea pig Adrenoceptors A pEC50 5.09 6.85 7.75 ChEMBL
β2 ADRB2 Guinea pig Adrenoceptors A pIC50 7.22 7.22 7.22 ChEMBL
β2 ADRB2 Human Adrenoceptors A pEC50 6.96 6.96 6.96 ChEMBL
β2 ADRB2 Human Adrenoceptors A pEC50 8.16 8.16 8.16 Drug Central
NPS NPSR1 Human Neuropeptide S A Potency 5.2 5.2 5.2 ChEMBL
β2 ADRB2 Guinea pig Adrenoceptors A pIC50 8.14 8.14 8.14 Drug Central