(-)-cyclazocine


SMILES Oc1ccc2c(c1)[C@]1(C)CCN([C@@H](C2)C1C)CC1CC1
InChIKey YQYVFVRQLZMJKJ-OTLVQASYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 271.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu1 GRM1 Rat Metabotropic glutamate C pKi 8.27 8.27 8.27 Guide to Pharmacology
mGlu1 GRM1 Rat Metabotropic glutamate C pKi 8.27 8.27 8.27 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu1 GRM1 Human Metabotropic glutamate C pIC50 8.29 8.29 8.29 ChEMBL
mGlu5 GRM5 Human Metabotropic glutamate C pIC50 5.16 5.16 5.16 ChEMBL
mGlu1 GRM1 Rat Metabotropic glutamate C pIC50 7.86 7.86 7.86 ChEMBL