DPDPE


SMILES None
InChIKey MCMMCRYPQBNCPH-WMIMKTLMSA-N
Sequence YXGFX

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Peptide
Endogenous/Surrogate Surrogate
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Human Orexin A pKi 8.4 8.97 9.1 Guide to Pharmacology
OX2 OX2R Human Orexin A pKi 8.9 9.35 9.1 Guide to Pharmacology
OX1 OX1R Human Orexin A pKi 8.54 8.72 9.2 ChEMBL
OX2 OX2R Human Orexin A pKi 9.52 9.56 9.7 ChEMBL
OX1 OX1R Rat Orexin A pKi 8.54 8.54 8.54 ChEMBL
OX2 OX2R Rat Orexin A pKi 9.51 9.51 9.51 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Human Orexin A pKB 8.7 8.7 8.7 Guide to Pharmacology
OX2 OX2R Human Orexin A pKB 9.7 9.7 9.7 Guide to Pharmacology
OX1 OX1R Mouse Orexin A pKB 7.6 7.6 7.6 Guide to Pharmacology
OX1 OX1R Rat Orexin A pKB 9.2 9.2 9.2 Guide to Pharmacology
OX2 OX2R Rat Orexin A pKB 9.6 9.6 9.6 Guide to Pharmacology
OX2 OX2R Mouse Orexin A pKB 8.2 8.2 8.2 Guide to Pharmacology
OX1 OX1R Human Orexin A pIC50 7.8 7.88 7.96 ChEMBL
OX2 OX2R Human Orexin A pIC50 7.77 7.87 7.96 ChEMBL