dynorphin A


SMILES None
InChIKey JMNJYGMAUMANNW-FIXZTSJVSA-N
Sequence YGGFLRRIRPKLKWDNQ

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Peptide
Endogenous/Surrogate Endogenous
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 9.3 9.3 9.3 Guide to Pharmacology
D2 DRD2 Rat Dopamine A pKi 6.85 6.85 6.85 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 8.77 8.77 8.77 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pEC50 8.18 8.18 8.18 ChEMBL