etorphine
SMILES | CCCC(C1CC23C=CC1(OC)C1C43CCN(C2Cc2c4c(O1)c(O)cc2)C)(O)C |
InChIKey | CAHCBJPUTCKATP-UHFFFAOYSA-N |
Chemical properties
Hydrogen bond acceptors | 5 |
Hydrogen bond donors | 2 |
Rotatable bonds | 4 |
Molecular weight (Da) | 411.2 |
Drug properties
Molecular type | Small molecule |
Physiological/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
δ | OPRD | Human | Opioid | A | pKi | 8.8 | 8.8 | 8.8 | Guide to Pharmacology |
κ | OPRK | Human | Opioid | A | pKi | 9.7 | 9.7 | 9.7 | Guide to Pharmacology |
μ | OPRM | Human | Opioid | A | pKi | 9.5 | 9.5 | 9.5 | Guide to Pharmacology |
μ | OPRM | Rat | Opioid | A | pKi | 8.22 | 8.76 | 9.3 | PDSP Ki database |
κ | OPRK | Human | Opioid | A | pKi | 9.74 | 9.74 | 9.74 | PDSP Ki database |
δ | A0A286XTF2 | Guinea pig | Opioid | A | pKi | 9.57 | 9.57 | 9.57 | PDSP Ki database |
μ | OPRM | Human | Opioid | A | pKi | 9.59 | 9.59 | 9.59 | PDSP Ki database |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |