etorphine


SMILES CCCC(C1CC23C=CC1(OC)C1C43CCN(C2Cc2c4c(O1)c(O)cc2)C)(O)C
InChIKey CAHCBJPUTCKATP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 4
Molecular weight (Da) 411.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 8.8 8.8 8.8 Guide to Pharmacology
κ OPRK Human Opioid A pKi 9.7 9.7 9.7 Guide to Pharmacology
μ OPRM Human Opioid A pKi 9.5 9.5 9.5 Guide to Pharmacology
μ OPRM Rat Opioid A pKi 8.22 8.76 9.3 PDSP Ki database
κ OPRK Human Opioid A pKi 9.74 9.74 9.74 PDSP Ki database
δ A0A286XTF2 Guinea pig Opioid A pKi 9.57 9.57 9.57 PDSP Ki database
μ OPRM Human Opioid A pKi 9.59 9.59 9.59 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database