CHEMBL4066435


SMILES COc1ccccc1N1CCN(CCCN2C(=O)COc3ccccc32)CC1
InChIKey NYPHNXBBMJRKSX-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 381.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.56 6.56 6.56 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.37 7.37 7.37 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MCH1 MCHR1 Human Melanin-concentrating hormone A pIC50 5.29 5.29 5.29 ChEMBL