CHEMBL4215875


SMILES Cc1ccc(-c2noc3c2CCNCC3)cc1
InChIKey HZUVTGUCSFHZGQ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 1
Molecular weight (Da) 228.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1E 5HT1E Human 5-Hydroxytryptamine A pKi 5.75 5.75 5.75 ChEMBL
5-HT5A 5HT5A Human 5-Hydroxytryptamine A pKi 5.95 5.95 5.95 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 6.83 6.83 6.83 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.79 7.79 7.8 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.82 6.82 6.82 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.31 6.31 6.31 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 7.7 7.7 7.7 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.86 6.86 6.86 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pIC50 6.07 6.07 6.07 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pEC50 7.39 7.39 7.39 ChEMBL