Chembl1253770


SMILES CCCN(CCN1CCN(c2ccc(-c3ccccc3)cc2)CC1)C1CCc2ccc(O)cc2C1
InChIKey MHNXSUUHELFLSP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 469.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections


Bioactivity

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Rat Dopamine A pKi 8.28 8.41 8.55 ChEMBL
D2 DRD2 Rat Dopamine A pKi 7.19 7.21 7.24 ChEMBL
D3 DRD3 Human Dopamine A pEC50 8.99 8.99 8.99 ChEMBL
D2 DRD2 Human Dopamine A pEC50 6.97 6.97 6.97 ChEMBL