CHEMBL124642


SMILES CCN(CC)C(=O)c1ccc(C(c2ccccc2)N2CCN(C)CC2)cc1
InChIKey ADYWDZJRWKEHMW-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 365.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Guinea pig Opioid A pKi 5.0 5.0 5.0 ChEMBL
μ OPRM Rat Opioid A pKi 5.0 5.0 5.0 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pEC50 6.68 6.68 6.68 ChEMBL
δ OPRD Human Opioid A pIC50 7.39 7.39 7.39 ChEMBL
κ OPRK Human Opioid A pIC50 5.16 5.16 5.16 ChEMBL