JTC-801


SMILES CCc1ccc(cc1)OCc1ccccc1C(=O)Nc1ccc2c(c1)c(N)cc(n2)C
InChIKey VTGBZWHPJFMTKS-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 6
Molecular weight (Da) 411.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
SMO SMO Human Frizzled F pIC50 8.3 8.3 8.3 Guide to Pharmacology
SMO SMO Human Frizzled F pIC50 8.08 8.08 8.08 Drug Central
SMO SMO Mouse Frizzled F pIC50 8.3 8.3 8.3 ChEMBL
SMO SMO Mouse Frizzled F pIC50 8.08 8.08 8.08 Drug Central