CHEMBL443546


SMILES CC(C)Oc1ccccc1N1CCN(Cc2cccc(CN3C(=O)CNC3=O)c2)CC1
InChIKey NMUHNFGAJWPHNN-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 422.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Rat Dopamine A pKi 7.64 7.64 7.64 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 8.11 8.11 8.11 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database