CHEMBL418854


SMILES COc1ccccc1N1CCC(CNCC2COc3ccc(Cl)cc3O2)CC1
InChIKey QHLRKDSRGUZHSH-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 402.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 7.57 7.57 7.57 ChEMBL
D2 DRD2 Rat Dopamine A pKi 7.36 7.36 7.36 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.15 7.15 7.15 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 7.66 7.66 7.66 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 7.24 7.24 7.24 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.8 8.8 8.8 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.44 8.44 8.44 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.88 7.88 7.88 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database