CHEMBL4203581


SMILES O=C(c1ccc(Cl)cc1)N1CCN(CCN2CCC3(C2)C(=O)Nc2ccccc23)CC1
InChIKey KSAJZUQQFWZUSQ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 438.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.28 6.28 6.28 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 5.11 5.11 5.11 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 4.76 4.76 4.76 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 4.32 4.32 4.32 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database