Chembl4460387
Chemical Properties
| SMILES | NC(=O)c1cccc([C@@H]2C[C@@H]3CC[C@H](C2)N3CCN(CC2CCCCC2)C(=O)Cc2nnn[nH]2)c1 |
| Hydrogen bond acceptors | 6 |
| Hydrogen bond donors | 2 |
| Rotatable bonds | 9 |
| Molecular weight | 479.3 |
Drug Properties
| Type | Small molecule |
| Endogenous | No |
| Approved | No |
| InChIKey | HNHKFDUWJZKHPK-NUNAXRQHSA-N |
Bioactivity
| Receptor | Experimental Data | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| κ | OPRK | Guinea pig | Opioid | A | pKi | 8.8 | 8.8 | 8.8 | ChEMBL |
| δ | OPRD | Human | Opioid | A | pKi | 8.5 | 8.5 | 8.5 | ChEMBL |
| μ | OPRM | Human | Opioid | A | pKi | 9.4 | 9.4 | 9.4 | ChEMBL |