CHEMBL4209274


SMILES Fc1ccc(-c2n[nH]c3c2CCNCC3)cc1
InChIKey YOZGUJJGVBYZQY-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 1
Molecular weight (Da) 231.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1E 5HT1E Human 5-Hydroxytryptamine A pKi 6.1 6.1 6.1 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 6.2 6.2 6.2 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.98 6.98 6.98 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.38 6.38 6.38 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 7.01 7.01 7.01 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.7 6.7 6.7 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.76 6.76 6.76 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.73 5.73 5.73 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pEC50 6.73 6.73 6.73 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pIC50 5.16 5.16 5.16 ChEMBL