GPCRdb

GABA

GABA

SMILES	NCCCC(=O)O
InChIKey	BTCSSZJGUNDROE-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	2
Hydrogen bond donors	2
Rotatable bonds	3
Molecular weight (Da)	103.1

Database connections

Guide To Pharmacology DrugBank Drug Central ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

CB₁	CNR1	Human	Cannabinoid	A	pKi	6.00	6.00	6.00	PDSP Ki database
D₁	DRD1	Rat	Dopamine	A	pKi	5.00	5.00	5.00	PDSP Ki database
D₂	DRD2	Rat	Dopamine	A	pKi	5.00	5.00	5.00	PDSP Ki database

Showing 1 to 3 of 3 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

GABA_B1	GABR1	Rat	GABA_B	C	pIC50	4.50	4.55	4.60	Guide to Pharmacology
GABA_B1	GABR1	Human	GABA_B	C	pEC50	5.77	5.77	5.77	ChEMBL
GABA_B1	GABR1	Rat	GABA_B	C	pIC50	8.34	8.34	8.34	Drug Central
NPS	NPSR1	Human	Neuropeptide S	A	Potency	4.50	4.50	4.50	ChEMBL
TSH	TSHR	Human	Glycoprotein hormone	A	Potency	4.50	4.50	4.50	ChEMBL

Showing 1 to 5 of 5 entries

GABA

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Endogenous
Approved drug	Yes

Clinical Trials

Phase I 0

Phase II 0

Phase III 0

Approved No

Database connections

Guide To Pharmacology DrugBank Drug Central ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.

This ligand is endogenous.