CHEMBL4213379


SMILES c1ccc(Cc2ccnc3c2CC[C@@H]2CNCCN32)cc1
InChIKey BCRYOGOFXLRJPN-MRXNPFEDSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 279.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 7.6 7.6 7.6 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 9.6 9.6 9.6 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.9 8.9 8.9 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pEC50 6.1 6.11 6.12 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pEC50 9.9 9.92 9.94 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pEC50 7.27 7.29 7.3 ChEMBL