galanin
SMILES | None |
InChIKey | WVFODTWUOPGPAP-CIJSCKBQSA-N |
Sequence | GWTLNSAGYLLGPHAIDNHRSFHDKYGLA |
Chemical properties
Hydrogen bond acceptors | None |
Hydrogen bond donors | None |
Rotatable bonds | None |
Molecular weight (Da) |
Drug properties
Molecular type | Peptide |
Physiological/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
GAL1 | GALR1 | Human | Galanin | A | pKd | 9.46 | 9.46 | 9.46 | Guide to Pharmacology |
GAL1 | GALR1 | Human | Galanin | A | pKi | 9.64 | 10.12 | 10.6 | Guide to Pharmacology |
GAL2 | GALR2 | Human | Galanin | A | pKi | 9.02 | 9.02 | 9.02 | Guide to Pharmacology |
GAL2 | GALR2 | Human | Galanin | A | pKd | 9.715 | 9.71 | 9.71 | Guide to Pharmacology |
GAL3 | GALR3 | Human | Galanin | A | pKi | 8.01 | 8.01 | 8.01 | Guide to Pharmacology |
GAL3 | GALR3 | Human | Galanin | A | pKd | 8.65 | 8.65 | 8.65 | Guide to Pharmacology |
GAL3 | GALR3 | Rat | Galanin | A | pKi | 8.14 | 8.14 | 8.14 | Guide to Pharmacology |
GAL3 | GALR3 | Rat | Galanin | A | pKd | 9.01 | 9.13 | 9.26 | Guide to Pharmacology |
GAL2 | GALR2 | Rat | Galanin | A | pKd | 8.4 | 9.14 | 9.89 | Guide to Pharmacology |
GAL2 | GALR2 | Rat | Galanin | A | pKi | 8.98 | 9.14 | 9.3 | Guide to Pharmacology |
GAL1 | GALR1 | Rat | Galanin | A | pKd | 9.52 | 9.62 | 10.72 | Guide to Pharmacology |
GAL1 | GALR1 | Rat | Galanin | A | pKi | 9.09 | 9.54 | 10.0 | Guide to Pharmacology |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
GAL1 | GALR1 | Human | Galanin | A | pIC50 | 9.8 | 9.82 | 9.85 | Guide to Pharmacology |
GAL2 | GALR2 | Human | Galanin | A | pIC50 | 9.46 | 9.46 | 9.46 | Guide to Pharmacology |
GAL2 | GALR2 | Human | Galanin | A | pEC50 | 8.09 | 8.09 | 8.09 | Guide to Pharmacology |
GAL3 | GALR3 | Human | Galanin | A | pIC50 | 7.92 | 7.92 | 7.92 | Guide to Pharmacology |
GAL2 | GALR2 | Rat | Galanin | A | pEC50 | 7.74 | 7.74 | 7.74 | Guide to Pharmacology |
GAL2 | GALR2 | Rat | Galanin | A | pIC50 | 9.34 | 9.38 | 9.43 | Guide to Pharmacology |
GAL1 | GALR1 | Rat | Galanin | A | pIC50 | 10.15 | 10.19 | 10.22 | Guide to Pharmacology |