CHEMBL447476


SMILES CNc1cc(OC)c(C(=O)N[C@H]2CCCN(Cc3ccccc3)C2)cc1Cl
InChIKey LGRVHISBHOARSB-INIZCTEOSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 6
Molecular weight (Da) 387.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Bovine Dopamine A pKi 5.0 5.12 5.25 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.19 7.39 7.6 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.82 6.04 6.25 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.6 6.73 6.89 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database