CHEMBL424204
SMILES | CCN(c1nc(C)nc(N2CCOCC2)n1)c1c(Br)cc(OC)cc1OC |
InChIKey | FKWFEXHQWCTXFD-UHFFFAOYSA-N |
Chemical properties
Hydrogen bond acceptors | 8 |
Hydrogen bond donors | 0 |
Rotatable bonds | 6 |
Molecular weight (Da) | 437.1 |
Drug properties
Molecular type | Small molecule |
Physiological/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
CRF1 | CRFR1 | Rat | Corticotropin-releasing factor | B1 | pKi | 7.37 | 7.37 | 7.37 | ChEMBL |
CRF1 | CRFR1 | Human | Corticotropin-releasing factor | B1 | pKi | 7.5 | 7.5 | 7.5 | ChEMBL |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |