CHEMBL4247275


SMILES O=c1[nH]c2c(N3CCN(CC[C@@H]4CCCN4S(=O)(=O)c4cncc5ccccc45)CC3)cccc2o1
InChIKey HACFIQPIDCCMMT-FQEVSTJZSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 507.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.17 6.17 6.17 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 5.52 5.52 5.52 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.69 5.69 5.69 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.57 7.57 7.57 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.3 8.3 8.3 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database